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Indications
Although the Pap smear may be done as part of the evaluation of a symptomatic
woman, it is usually collected for screening purposes.
The various organizations for disease prevention and health promotion disagree
on how frequently women should have Pap smear screening and at what ages
screening should begin and end. The rationale for different recommendations
may be found in the background section. The
guidelines of the American College of Physicians (ACP), the United States
Preventive Services Task Force (USPSTF), the Canadian Task Force on the
Periodic Health Examination (CTF), and others are summarized in the following
table. The major difference among them is the recommended screening interval
after age 35. Click on the organization names for more information about
each guideline.
| <--------------------Age--------------------> |
| Organiztion |
<35* | 38 | 40 | 41 | 44 |
45 | 47 | 50 | 53 | 55 | 56 | 59 | 60 | 62 |
65 | >65* | | CTF | X |
| X | | | X | | X | | X
| | | X | | X | | | ACP | X
| X | | X | X | | X | X | X |
| X | X | | X | X | | | USPTF |
X | X | | X | X | | X | X | X |
| X | X | | X | X | | | Other |
X | X | | X | X | | X | X | X |
| X | X | | X | X | |
| Eddy).
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Women at higher risk for cervical cancer
The recommendations for women who are at higher risk for cervical cancer
are controversial. Risk factors include young age at first intercourse,
smoking, use of oral contraceptives (Eddy, Kjaer), multiparity (Miller), human papilloma virus (Lieu), low socioeconomic status (Brinton), HIV infection (Hankins), advancing age, high lifetime number
of male sexual partners, promiscuity of the sexual partner, and having
a sexual partner with penile cancer (Lichtman).
Certain ethnic groups, particularly blacks, Hispanics, and Native Americans,
have higher rates of cervical cancer (Eddy).
Women who do not receive regular Pap testing are also at higher risk for
cervical cancer. Incomplete Pap testing is more common among blacks, the
poor, the uninsured, the elderly, and those living in rural areas (USPSTF). Some groups, such as the Canadian Task
Force, propose incorporating risk factors into recommendations for screening
frequency. Thus far, there are no recommended guidelines for screening
such women.
Women who have had a hysterectomy The Pap screening recommendations for women
who have had a hysterectomy differ from the recommendations for women with an intact cervix.
The 1996 U.S. Preventive Services Task Force recommends Pap testing after hysterectomy if:
- The cervix was left behind at surgery
- The hysterectomy was performed because of cervical cancer
The Canadian Task Force suggests NO screening post-hysterectomy if:
- The hysterectomy was for a benign condition, AND
- There was pathologic documentation that the cervical epithelium had been completely
removed, AND
- Smears before surgery were normal (Miller).
"No widely accepted Pap smear screening protocol after hysterectomy
has been formulated, and the effectiveness of Pap smear screening for
vaginal cancer is not well-substantiated" (McIntosh). Pearce reported that "the prevalence
of abnormal findings on cytopathological examination of vaginal Papanicolaou
smears after hysterectomy for benign gynecologic disease is extremely
low" (Pearce). It may therefor, be more valuable to identify
women who are at higher risk for vaginal cancer. A history of previous
abnormal Pap smear of either the cervix or vagina places women in a higher
risk group (McIntosh). Women who still have a cervix certainly
warrant continued Pap testing for cervical cancer. If the woman’s hysterectomy
was done before about 1960, she is likely to still have a cervix because
of the type of procedure that was done. It is also important to identify
if post-hysterectomy women have remaining ovary(ies), as about 5% of ovarian
cancers occur in women with previous hysterectomy (McIntosh).
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American College of Physicians Screening
Recommendations
The American College of Physicians (1991) recommends Pap smears every 3 years for women aged 20 to 65
Contraindications
If a pelvic examination can be safely done, there are no absolute contraindications to doing a Papanicolaou (Pap) smear. However, there are some circumstances when you should avoid doing a Pap Smear because it may make interpreting the smear impossible. For example, doing a Pap smear during menses may interfere with interpretation because the blood may obscure the other cells.
Click here to review the contraindications for pelvic examination.
Canadian Task Force Screening
Recommendations
The Canadian Task Force on the Periodic Health Examination (1991) suggests Pap smears every 3 years before age 35 and every 5 years to age 74, after two normal annual smears following the onset of sexual activity.
Other Screening Recommendations
In 1993 the American Cancer Society, National Cancer Institute, American College of Obstetricians and Gynecologists, American Medical Association, and American Academy of Family Physicians, among others, came to a consensus that "all women who are or have been sexually active, or who have reached age 18, should have annual Pap smears." After three or more annual smears have been normal, the recommendation allows for less frequent screening "at the discretion of the physician." When to stop screening is less well defined.
Paul S. Frame M.D., (1986) suggests that a Pap smear be done every 2 years after two annual smears on all sexually active women under age 70.
Note: women's health
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