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Heat exhaustion & heat stroke
OVERVIEW: A continuum of increasingly severe heat illnesses caused by dehydration, electrolyte losses, and failure of the body's thermoregulatory mechanisms • Heat exhaustion is an acute heat injury with hyperthermia due to dehydration • Heat stroke is extreme hyperthermia with thermoregulatory failure and profound central nervous system dysfunction System(s) affected: Endocrine/Metabolic, Nervous Genetics: N/A Incidence/Prevalence in USA: Dependent on predisposing conditions in combination with environmental factors Predominant age: More likely in children or elderly Predominant sex: Male = Female SIGNS AND SYMPTOMS: • Heat Exhaustion • Fatigue and lethargy • Weakness • Dizziness • Nausea, vomiting • Myalgias • Headache • Profuse sweating • Tachycardia • Hypotension • Lack of coordination • Agitation • Intense thirst • Hyperventilation • Paresthesias • Core temperature elevated but < 103°F (< 39.4°C) • Heat Stroke • Exhaustion • Confusion, disorientation • Coma • Hot, flushed, dry skin • Core temperature > 105°F (> 40.5°C) CAUSES: Failure of heat-dissipating mechanisms or an overwhelming heat stress leading to a rise in core temperature, dehydration and salt depletion RISK FACTORS: • Poor acclimatization to heat or poor physical conditioning • Salt or water depletion • Obesity • Acute febrile or gastrointestinal illnesses • Chronic illnesses - uncontrolled diabetes or hypertension, cardiac disease • Alcohol and other substance abuse • High heat and humidity, poor air circulation in environment • Heavy, restrictive clothing DIAGNOSIS DIFFERENTIAL DIAGNOSIS: • Other causes of elevated temperature, dehydration or circulatory collapse • Febrile illnesses, sepsis • Drug-induced fluid loss • Cardiac arrhythmia or infarction • Acute cocaine intoxication • Malignant hyperthermia (an autosomally inherited disorder of skeletal and cardiac muscle in which patients have abnormal muscle metabolism on exposure to halothane or skeletal muscle reactants) LABORATORY: • Used primarily to detect end-organ damage • Electrolytes, urinalysis • Creatinine, blood urea nitrogen • Liver enzymes • Complete blood count • Increased urine specific gravity • Results of above studies yield hypernatremia, hyperchloremia, hemoconcentration Drugs that may alter lab results: Diuretics Disorders that may alter lab results: N/A PATHOLOGICAL FINDINGS: Only those associated with major organ system failure SPECIAL TESTS: N/A IMAGING: N/A DIAGNOSTIC PROCEDURES: Rectal temperature monitoring TREATMENT APPROPRIATE HEALTH CARE: Emergency treatment - best in a hospital setting GENERAL MEASURES: • Rapid cooling - remove clothing, wet patient down, ice packs • Fluid and electrolyte replacement with hypotonic oral fluids or IV 0.5-1.0 liter normal saline • Consider central venous pressure monitoring SURGICAL MEASURES: N/A ACTIVITY: Rest with legs elevated DIET: • Cool or cold clear liquids only (non-carbonated) • Avoid caffeine • Unrestricted sodium PATIENT EDUCATION: • Stress the importance of proper conditioning and acclimatization • Instruct patients to recognize heat stress signs and symptoms • Maintain as much skin exposure as possible in hot, humid conditions, while using proper sun block protection • Avoid dehydration with proper fluids during activity or exercise - 8 oz fluid intake for every 15 minutes of moderate exercise MEDICATIONS DRUG(S) OF CHOICE: No medications are required in the initial management. Use isotonic saline solution to rehydrate. Contraindications: N/A Precautions: N/A Significant possible interactions: N/A ALTERNATIVE DRUGS: N/A FOLLOW UP PATIENT MONITORING: • Rectal temperature monitoring - cooling may be discontinued when the core temperature drops to 102°F (38.9°C) and stabilizes • Heat stroke patients may require airway management, hemodynamic monitoring and careful fluid and electrolyte administration and monitoring • Consider central venous pressure monitoring PREVENTION/AVOIDANCE: Most important factor in preventing heat stress is adequate fluid replacement. Allow acclimatization to hot weather through proper conditioning and activity modification. Dress appropriately with loose-fitting, open weave, light-colored clothing. POSSIBLE COMPLICATIONS: • May involve failure of any major organ system • Cardiac arrhythmias or infarction • Pulmonary edema, adult respiratory distress syndrome • Coma, seizures • Acute renal failure • Rhabdomyolysis • Disseminated intravascular coagulation • Hepatocellular necrosis EXPECTED COURSE AND PROGNOSIS: • Good when mental function is not altered and when serum enzymes are not elevated. Recovery is within 24-48 hours in most cases. • The mortality rate for heat stroke (10-80%) is directly related to the duration and intensity of hyperthermia as well as to the speed and effectiveness of diagnosis and treatment MISCELLANEOUS ASSOCIATED CONDITIONS: N/A AGE-RELATED FACTORS: Pediatric: Children are more susceptible Geriatric: Elderly are more susceptible Others: N/A PREGNANCY: May be more prone to volume depletion with heat stress SYNONYMS: • Heat illness • Heat injury • Hyperthermia • Heat collapse • Heat prostration ICD-9-CM: 992.5 Heat exhaustion 992.0 Heat stroke
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